hier ein Auszug aus der ReadMe:
Also auf gut deutsch: die Dateien skse_steam_loader.dll, skse_1_3.dll und skse_loader.exe in dein Verzeichnis ...Steam\SteamApps\common\skyrim\SKSE will support the latest version of Skyrim available on Steam, and _only_ this version (currently 220.127.116.11). When a new version is released, we will update as soon as possible; please be patient. No editor has been released yet.
[ Installation ]
1. Copy the .dll and .exe files to your Skyrim directory. This is usually in your Program Files folder under Steam\SteamApps\common\skyrim\. If you see files named TESV and SkyrimLauncher, this is the correct folder. Do not copy these files to the Data folder as with a normal mod. The "src" folder is only useful for programmers, most users can ignore it.
2. Launch the game via running skse_loader.exe.